macOS uses ⌘ (Command); on Windows use Ctrl in its place. ⇧ is Shift, ⌥ is Alt/Option. The same list is in the app under Help ▸ Keyboard Shortcuts (⌘/).
Files
Action
Shortcut
New file
⌘N
Open…
⌘O
Save
⌘S
Save As…
⌘⇧S
Close file
⌘W
Find in file (Edit ▸ Find in File…: pages, cards, PDFs, video notes)
⌘F
Walk the hits · jump · close
↑ / ↓ · Return · Esc
The User Guide (Help ▸ User Guide: the manual as a canvas, a frame per section) — on its Keyboard Shortcuts page
⌘/
View
Action
Shortcut
Zoom in / out (the page, a PDF, or the canvas — whichever is in front)
⌘+ / ⌘−
Zoom to 100%
⌘0
In a page: toggle Full Width · on the canvas: fit everything
⌘1
Always on Top — the window above every other app’s (the toolbar’s pin)
⌥⌘T
Back / Forward through the views you visited (canvas, page, frame, file) — also the chevrons left of the path and the mouse’s back / forward buttons
⌥⌘← / ⌥⌘→
Zoom about the pointer
⌘-wheel, or pinch
Pan the canvas with the hand
hold Space and drag
Pan anywhere
middle-button drag
Canvas
Action
Shortcut
Select / Hand / Page / Frame tools
V / H / N / F
Group the selection in a frame (with one frame selected: add the rest to it) · Ungroup
⌘G · ⌘⇧G
Drag an element INTO a frame (it lights) or OUT of its frame — the plain drag only moves
⌘ held at the release
Text box · plain text
T · ⇧T
Pen / Rectangle / Oval / Line / Arrow / Eraser
P / R / O / L / A / E
Open the selected element — the page view, the studio, the PDF view, an image’s lightbox
double-click · Return · the open glyph
Preview the selected image, video, PDF or audio in the lightbox (‹ › or ← / → step through them; PageUp / PageDown page a PDF)
Space or Return (Space or Esc closes)
Cancel a stroke → drop the tool → clear the selection
Esc (repeat)
Delete the selection
Delete / Backspace
Add / remove one from the selection
⇧Click
Select several (marquee)
drag on empty canvas
Paste files, an image, text or a link as cards
⌘V
Page a selected PDF
PageUp / PageDown
Step the selection forward / back one layer
⌘] / ⌘[
Bring to front / send to back
⌥⌘] / ⌥⌘[
PDF View (full-window)
Action
Shortcut
Pen / Rectangle / Oval / Line / Arrow / Eraser (strokes stay on that page)
P / R / O / L / A / E
Back to the pointer
V
Scroll with the hand while a tool is armed
hold Space and drag
Undo / redo a stroke
⌘Z / ⌘⇧Z
Drop the tool → back to the canvas
Esc (repeat)
Editing
Action
Shortcut
Undo (the page’s or the canvas’s history)
⌘Z
Redo
⌘⇧Z or ⌘Y
Cut / Copy / Paste
⌘X / ⌘C / ⌘V
Copy as Markdown
⌘⇧C
Insert a choice chip (To do / Doing / Done)
⌥⌘C
Indent / outdent a list item
Tab / ⇧Tab, or ⌘] / ⌘[
Next / previous lane (in a split row)
Tab / ⇧Tab
New line in a code block (Enter on a blank last line exits)
⇧Enter
Step out of the page to the canvas (nothing selected)
Esc
Inline Formatting
Action
Shortcut
Bold
⌘B
Italic
⌘I
Underline
⌘U
Strikethrough
⌘⇧X
Inline code
⌘E
Link
⌘K
Highlight (toggle the armed colour)
⌘⇧H
Clear formatting
⌘\
Tables
Action
Shortcut
Next / previous cell (adds a row past the last cell)
Tab / ⇧Tab
Down the column (the last row adds one; an empty last row leaves the table)
Enter
Insert a row below
⌘Enter
Cycle a checkmark cell
Space
Select the block → its cell → the table → the page
⌘A (repeat)
Whole row or column (on a grip)
Click
Span of rows or columns (on a grip)
⇧Click
Add / remove a row or column (on a grip)
⌘Click
Copy a grip selection as a table
⌘C
Clear a grip selection’s contents
Backspace / Delete
A selected row → the whole table → the caret below it
Esc
Video (the studio, an inline video with the caret, or a selected card)
Action
Shortcut
Play / pause (Space too, in the studio — elsewhere Space is the lightbox)